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Differentiate w.r.t. b
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\frac{4^{1}a^{2}b^{5}}{8^{1}a^{6}b^{2}}
Use the rules of exponents to simplify the expression.
\frac{4^{1}}{8^{1}}a^{2-6}b^{5-2}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{4^{1}}{8^{1}}a^{-4}b^{5-2}
Subtract 6 from 2.
\frac{4^{1}}{8^{1}}\times \frac{1}{a^{4}}b^{3}
Subtract 2 from 5.
\frac{1}{2}\times \frac{1}{a^{4}}b^{3}
Reduce the fraction \frac{4}{8} to lowest terms by extracting and canceling out 4.