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\frac{4\left(5x-1\right)}{\left(5x-1\right)\left(2x+1\right)}-\frac{2\left(2x+1\right)}{\left(5x-1\right)\left(2x+1\right)}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of 2x+1 and 5x-1 is \left(5x-1\right)\left(2x+1\right). Multiply \frac{4}{2x+1} times \frac{5x-1}{5x-1}. Multiply \frac{2}{5x-1} times \frac{2x+1}{2x+1}.
\frac{4\left(5x-1\right)-2\left(2x+1\right)}{\left(5x-1\right)\left(2x+1\right)}
Since \frac{4\left(5x-1\right)}{\left(5x-1\right)\left(2x+1\right)} and \frac{2\left(2x+1\right)}{\left(5x-1\right)\left(2x+1\right)} have the same denominator, subtract them by subtracting their numerators.
\frac{20x-4-4x-2}{\left(5x-1\right)\left(2x+1\right)}
Do the multiplications in 4\left(5x-1\right)-2\left(2x+1\right).
\frac{16x-6}{\left(5x-1\right)\left(2x+1\right)}
Combine like terms in 20x-4-4x-2.
\frac{16x-6}{10x^{2}+3x-1}
Expand \left(5x-1\right)\left(2x+1\right).