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Differentiate w.r.t. x
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\frac{36x^{-2}y^{5}z^{-11}}{3z^{4}x^{-3}}
To multiply powers of the same base, add their exponents. Add -6 and 3 to get -3.
\frac{12z^{-11}x^{-2}y^{5}}{x^{-3}z^{4}}
Cancel out 3 in both numerator and denominator.
\frac{12z^{-11}x^{1}y^{5}}{z^{4}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{12x^{1}y^{5}}{z^{15}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{12xy^{5}}{z^{15}}
Calculate x to the power of 1 and get x.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{36y^{5}}{z^{11}\times 3x^{3}z^{4}}x^{-2-\left(-6\right)})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{12y^{5}}{x^{3}z^{15}}x^{4})
Do the arithmetic.
4\times \frac{12y^{5}}{x^{3}z^{15}}x^{4-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\frac{48y^{5}}{x^{3}z^{15}}x^{3}
Do the arithmetic.