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Differentiate w.r.t. x
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\frac{3x^{1}y\times 18y^{-1}}{9x^{-4}y^{-3}}
To multiply powers of the same base, add their exponents. Add 2 and -1 to get 1.
\frac{3x^{1}\times 18}{9x^{-4}y^{-3}}
Multiply y and y^{-1} to get 1.
\frac{6x^{1}}{x^{-4}y^{-3}}
Cancel out 3\times 3 in both numerator and denominator.
\frac{6x^{5}}{y^{-3}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{54y}{xy\times \frac{9}{y^{3}}}x^{2-\left(-4\right)})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{6y^{3}}{x}x^{6})
Do the arithmetic.
6\times \frac{6y^{3}}{x}x^{6-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\frac{36y^{3}}{x}x^{5}
Do the arithmetic.