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Differentiate w.r.t. x
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\frac{\mathrm{d}}{\mathrm{d}x}(\frac{3}{y^{3}}x^{-4-3})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{3}{y^{3}}x^{-7})
Do the arithmetic.
-7\times \frac{3}{y^{3}}x^{-7-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-\frac{21}{y^{3}}\right)x^{-8}
Do the arithmetic.
\frac{3y^{-3}}{x^{7}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.