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\frac{3}{\left(x-8\right)\left(x+8\right)}-\frac{4}{5\left(x-8\right)}
Factor x^{2}-64. Factor 5x-40.
\frac{3\times 5}{5\left(x-8\right)\left(x+8\right)}-\frac{4\left(x+8\right)}{5\left(x-8\right)\left(x+8\right)}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of \left(x-8\right)\left(x+8\right) and 5\left(x-8\right) is 5\left(x-8\right)\left(x+8\right). Multiply \frac{3}{\left(x-8\right)\left(x+8\right)} times \frac{5}{5}. Multiply \frac{4}{5\left(x-8\right)} times \frac{x+8}{x+8}.
\frac{3\times 5-4\left(x+8\right)}{5\left(x-8\right)\left(x+8\right)}
Since \frac{3\times 5}{5\left(x-8\right)\left(x+8\right)} and \frac{4\left(x+8\right)}{5\left(x-8\right)\left(x+8\right)} have the same denominator, subtract them by subtracting their numerators.
\frac{15-4x-32}{5\left(x-8\right)\left(x+8\right)}
Do the multiplications in 3\times 5-4\left(x+8\right).
\frac{-17-4x}{5\left(x-8\right)\left(x+8\right)}
Combine like terms in 15-4x-32.
\frac{-17-4x}{5x^{2}-320}
Expand 5\left(x-8\right)\left(x+8\right).