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Differentiate w.r.t. x
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\frac{3^{-3}y^{-5}}{5^{-2}y^{-2}x^{5}}
Cancel out x^{2} in both numerator and denominator.
\frac{3^{-3}}{5^{-2}y^{3}x^{5}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{\frac{1}{27}}{5^{-2}y^{3}x^{5}}
Calculate 3 to the power of -3 and get \frac{1}{27}.
\frac{\frac{1}{27}}{\frac{1}{25}y^{3}x^{5}}
Calculate 5 to the power of -2 and get \frac{1}{25}.
\frac{1}{27\times \frac{1}{25}y^{3}x^{5}}
Express \frac{\frac{1}{27}}{\frac{1}{25}y^{3}x^{5}} as a single fraction.
\frac{1}{\frac{27}{25}y^{3}x^{5}}
Multiply 27 and \frac{1}{25} to get \frac{27}{25}.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{1}{27y^{5}\times \frac{1}{25y^{2}}}x^{2-7})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{25}{27y^{3}}x^{-5})
Do the arithmetic.
-5\times \frac{25}{27y^{3}}x^{-5-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-\frac{125}{27y^{3}}\right)x^{-6}
Do the arithmetic.