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Evaluate
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Differentiate w.r.t. E
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\frac{5E^{-4}}{2\times 5^{-3}E^{-8}}
Cancel out 5 in both numerator and denominator.
\frac{5^{4}E^{4}}{2}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{625E^{4}}{2}
Calculate 5 to the power of 4 and get 625.
\frac{\mathrm{d}}{\mathrm{d}E}(\frac{25}{\frac{2}{25}}E^{-4-\left(-8\right)})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}E}(\frac{625}{2}E^{4})
Do the arithmetic.
4\times \frac{625}{2}E^{4-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
1250E^{3}
Do the arithmetic.