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Differentiate w.r.t. x
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\frac{24^{1}x^{2}y^{5}}{6^{1}x^{\frac{4}{3}}y^{\frac{3}{4}}}
Use the rules of exponents to simplify the expression.
\frac{24^{1}}{6^{1}}x^{2-\frac{4}{3}}y^{5-\frac{3}{4}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{24^{1}}{6^{1}}x^{\frac{2}{3}}y^{5-\frac{3}{4}}
Subtract \frac{4}{3} from 2.
\frac{24^{1}}{6^{1}}x^{\frac{2}{3}}y^{\frac{17}{4}}
Subtract \frac{3}{4} from 5.
4x^{\frac{2}{3}}y^{\frac{17}{4}}
Divide 24 by 6.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{24y^{5}}{6y^{\frac{3}{4}}}x^{2-\frac{4}{3}})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(4y^{\frac{17}{4}}x^{\frac{2}{3}})
Do the arithmetic.
\frac{2}{3}\times 4y^{\frac{17}{4}}x^{\frac{2}{3}-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\frac{8y^{\frac{17}{4}}}{3}x^{-\frac{1}{3}}
Do the arithmetic.