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Evaluate
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Differentiate w.r.t. x
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\frac{2x^{-5}y^{-3}z^{2}}{3x^{-2}z^{-2}y^{3}}
Cancel out 12 in both numerator and denominator.
\frac{2x^{-5}y^{-3}z^{4}}{3x^{-2}y^{3}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{2z^{4}}{3x^{3}y^{6}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{24z^{2}}{y^{3}\times \frac{36y^{3}}{z^{2}}}x^{-5-\left(-2\right)})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{2z^{4}}{3y^{6}}x^{-3})
Do the arithmetic.
-3\times \frac{2z^{4}}{3y^{6}}x^{-3-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-\frac{2z^{4}}{y^{6}}\right)x^{-4}
Do the arithmetic.