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45\times 220=x\times 450
Variable x cannot be equal to 0 since division by zero is not defined. Multiply both sides of the equation by 45x, the least common multiple of x,45.
9900=x\times 450
Multiply 45 and 220 to get 9900.
x\times 450=9900
Swap sides so that all variable terms are on the left hand side.
x=\frac{9900}{450}
Divide both sides by 450.
x=22
Divide 9900 by 450 to get 22.