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Differentiate w.r.t. x
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\frac{\mathrm{d}}{\mathrm{d}x}(\frac{20z^{9}y^{11}}{4y^{3}z^{8}}x^{9-4})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(5zy^{8}x^{5})
Do the arithmetic.
5\times 5zy^{8}x^{5-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
25zy^{8}x^{4}
Do the arithmetic.
5zx^{5}y^{8}
Cancel out 4y^{3}x^{4}z^{8} in both numerator and denominator.