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Evaluate
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Differentiate w.r.t. x
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\frac{x^{-2}y^{-2}}{8x^{-12}y^{2}}
Cancel out 2 in both numerator and denominator.
\frac{y^{-2}x^{10}}{8y^{2}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{x^{10}}{8y^{4}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{2}{y^{2}\times 16y^{2}}x^{-2-\left(-12\right)})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{1}{8y^{4}}x^{10})
Do the arithmetic.
10\times \frac{1}{8y^{4}}x^{10-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\frac{5}{4y^{4}}x^{9}
Do the arithmetic.