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Differentiate w.r.t. b
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\frac{2a^{-3}b^{4}}{4^{-1}\left(a^{2}\right)^{-1}\left(b^{-5}\right)^{-1}}
Expand \left(4a^{2}b^{-5}\right)^{-1}.
\frac{2a^{-3}b^{4}}{4^{-1}a^{-2}\left(b^{-5}\right)^{-1}}
To raise a power to another power, multiply the exponents. Multiply 2 and -1 to get -2.
\frac{2a^{-3}b^{4}}{4^{-1}a^{-2}b^{5}}
To raise a power to another power, multiply the exponents. Multiply -5 and -1 to get 5.
\frac{2a^{-3}b^{4}}{\frac{1}{4}a^{-2}b^{5}}
Calculate 4 to the power of -1 and get \frac{1}{4}.
\frac{2a^{-3}}{\frac{1}{4}a^{-2}b}
Cancel out b^{4} in both numerator and denominator.
\frac{2}{\frac{1}{4}ba^{1}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{2}{\frac{1}{4}ba}
Calculate a to the power of 1 and get a.