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\frac{2}{3}\left(-4+\frac{3}{4}\left(\frac{10}{6}-\frac{5}{6}\right)-\frac{3}{4}\left(\frac{5}{2}-1\right)\right)-\frac{4}{3}
Least common multiple of 3 and 6 is 6. Convert \frac{5}{3} and \frac{5}{6} to fractions with denominator 6.
\frac{2}{3}\left(-4+\frac{3}{4}\times \frac{10-5}{6}-\frac{3}{4}\left(\frac{5}{2}-1\right)\right)-\frac{4}{3}
Since \frac{10}{6} and \frac{5}{6} have the same denominator, subtract them by subtracting their numerators.
\frac{2}{3}\left(-4+\frac{3}{4}\times \frac{5}{6}-\frac{3}{4}\left(\frac{5}{2}-1\right)\right)-\frac{4}{3}
Subtract 5 from 10 to get 5.
\frac{2}{3}\left(-4+\frac{3\times 5}{4\times 6}-\frac{3}{4}\left(\frac{5}{2}-1\right)\right)-\frac{4}{3}
Multiply \frac{3}{4} times \frac{5}{6} by multiplying numerator times numerator and denominator times denominator.
\frac{2}{3}\left(-4+\frac{15}{24}-\frac{3}{4}\left(\frac{5}{2}-1\right)\right)-\frac{4}{3}
Do the multiplications in the fraction \frac{3\times 5}{4\times 6}.
\frac{2}{3}\left(-4+\frac{5}{8}-\frac{3}{4}\left(\frac{5}{2}-1\right)\right)-\frac{4}{3}
Reduce the fraction \frac{15}{24} to lowest terms by extracting and canceling out 3.
\frac{2}{3}\left(-\frac{32}{8}+\frac{5}{8}-\frac{3}{4}\left(\frac{5}{2}-1\right)\right)-\frac{4}{3}
Convert -4 to fraction -\frac{32}{8}.
\frac{2}{3}\left(\frac{-32+5}{8}-\frac{3}{4}\left(\frac{5}{2}-1\right)\right)-\frac{4}{3}
Since -\frac{32}{8} and \frac{5}{8} have the same denominator, add them by adding their numerators.
\frac{2}{3}\left(-\frac{27}{8}-\frac{3}{4}\left(\frac{5}{2}-1\right)\right)-\frac{4}{3}
Add -32 and 5 to get -27.
\frac{2}{3}\left(-\frac{27}{8}-\frac{3}{4}\left(\frac{5}{2}-\frac{2}{2}\right)\right)-\frac{4}{3}
Convert 1 to fraction \frac{2}{2}.
\frac{2}{3}\left(-\frac{27}{8}-\frac{3}{4}\times \frac{5-2}{2}\right)-\frac{4}{3}
Since \frac{5}{2} and \frac{2}{2} have the same denominator, subtract them by subtracting their numerators.
\frac{2}{3}\left(-\frac{27}{8}-\frac{3}{4}\times \frac{3}{2}\right)-\frac{4}{3}
Subtract 2 from 5 to get 3.
\frac{2}{3}\left(-\frac{27}{8}-\frac{3\times 3}{4\times 2}\right)-\frac{4}{3}
Multiply \frac{3}{4} times \frac{3}{2} by multiplying numerator times numerator and denominator times denominator.
\frac{2}{3}\left(-\frac{27}{8}-\frac{9}{8}\right)-\frac{4}{3}
Do the multiplications in the fraction \frac{3\times 3}{4\times 2}.
\frac{2}{3}\times \frac{-27-9}{8}-\frac{4}{3}
Since -\frac{27}{8} and \frac{9}{8} have the same denominator, subtract them by subtracting their numerators.
\frac{2}{3}\times \frac{-36}{8}-\frac{4}{3}
Subtract 9 from -27 to get -36.
\frac{2}{3}\left(-\frac{9}{2}\right)-\frac{4}{3}
Reduce the fraction \frac{-36}{8} to lowest terms by extracting and canceling out 4.
\frac{2\left(-9\right)}{3\times 2}-\frac{4}{3}
Multiply \frac{2}{3} times -\frac{9}{2} by multiplying numerator times numerator and denominator times denominator.
\frac{-9}{3}-\frac{4}{3}
Cancel out 2 in both numerator and denominator.
-3-\frac{4}{3}
Divide -9 by 3 to get -3.
-\frac{9}{3}-\frac{4}{3}
Convert -3 to fraction -\frac{9}{3}.
\frac{-9-4}{3}
Since -\frac{9}{3} and \frac{4}{3} have the same denominator, subtract them by subtracting their numerators.
-\frac{13}{3}
Subtract 4 from -9 to get -13.