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Differentiate w.r.t. x
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\frac{16}{\frac{130^{-3}}{x}}y
Calculate 2 to the power of 4 and get 16.
\frac{16}{\frac{\frac{1}{2197000}}{x}}y
Calculate 130 to the power of -3 and get \frac{1}{2197000}.
\frac{16}{\frac{1}{2197000x}}y
Express \frac{\frac{1}{2197000}}{x} as a single fraction.
16\times 2197000xy
Divide 16 by \frac{1}{2197000x} by multiplying 16 by the reciprocal of \frac{1}{2197000x}.
35152000xy
Multiply 16 and 2197000 to get 35152000.