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Differentiate w.r.t. a
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\frac{2^{-3}}{4^{-3}b^{1}a^{3}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{\frac{1}{8}}{4^{-3}b^{1}a^{3}}
Calculate 2 to the power of -3 and get \frac{1}{8}.
\frac{\frac{1}{8}}{\frac{1}{64}b^{1}a^{3}}
Calculate 4 to the power of -3 and get \frac{1}{64}.
\frac{\frac{1}{8}}{\frac{1}{64}ba^{3}}
Calculate b to the power of 1 and get b.
\frac{1}{8\times \frac{1}{64}ba^{3}}
Express \frac{\frac{1}{8}}{\frac{1}{64}ba^{3}} as a single fraction.
\frac{1}{\frac{1}{8}ba^{3}}
Multiply 8 and \frac{1}{64} to get \frac{1}{8}.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{1}{8b^{2}\times \frac{1}{64b}}a^{-1-2})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{8}{b}a^{-3})
Do the arithmetic.
-3\times \frac{8}{b}a^{-3-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-\frac{24}{b}\right)a^{-4}
Do the arithmetic.