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Differentiate w.r.t. m
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\frac{\mathrm{d}}{\mathrm{d}m}(\frac{16p^{18}n^{28}}{4p^{9}n^{14}}m^{36-18})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}m}(4p^{9}n^{14}m^{18})
Do the arithmetic.
18\times 4p^{9}n^{14}m^{18-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
72p^{9}n^{14}m^{17}
Do the arithmetic.
4p^{9}n^{14}m^{18}
Cancel out 4p^{9}n^{14}m^{18} in both numerator and denominator.