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\frac{\left(16-25x^{2}\right)\left(9x^{2}-y\right)}{\left(3x+y\right)\left(4x-5x^{2}\right)}
Divide \frac{16-25x^{2}}{3x+y} by \frac{4x-5x^{2}}{9x^{2}-y} by multiplying \frac{16-25x^{2}}{3x+y} by the reciprocal of \frac{4x-5x^{2}}{9x^{2}-y}.
\frac{\left(-5x-4\right)\left(5x-4\right)\left(9x^{2}-y\right)}{x\left(-5x+4\right)\left(3x+y\right)}
Factor the expressions that are not already factored.
\frac{-\left(-5x-4\right)\left(-5x+4\right)\left(9x^{2}-y\right)}{x\left(-5x+4\right)\left(3x+y\right)}
Extract the negative sign in -4+5x.
\frac{-\left(-5x-4\right)\left(9x^{2}-y\right)}{x\left(3x+y\right)}
Cancel out -5x+4 in both numerator and denominator.
\frac{45x^{3}+36x^{2}-5xy-4y}{3x^{2}+xy}
Expand the expression.
\frac{\left(16-25x^{2}\right)\left(9x^{2}-y\right)}{\left(3x+y\right)\left(4x-5x^{2}\right)}
Divide \frac{16-25x^{2}}{3x+y} by \frac{4x-5x^{2}}{9x^{2}-y} by multiplying \frac{16-25x^{2}}{3x+y} by the reciprocal of \frac{4x-5x^{2}}{9x^{2}-y}.
\frac{\left(-5x-4\right)\left(5x-4\right)\left(9x^{2}-y\right)}{x\left(-5x+4\right)\left(3x+y\right)}
Factor the expressions that are not already factored.
\frac{-\left(-5x-4\right)\left(-5x+4\right)\left(9x^{2}-y\right)}{x\left(-5x+4\right)\left(3x+y\right)}
Extract the negative sign in -4+5x.
\frac{-\left(-5x-4\right)\left(9x^{2}-y\right)}{x\left(3x+y\right)}
Cancel out -5x+4 in both numerator and denominator.
\frac{45x^{3}+36x^{2}-5xy-4y}{3x^{2}+xy}
Expand the expression.