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Differentiate w.r.t. t
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\frac{5\times 25\times 1^{-2}\times \frac{1}{10}}{4^{-3}t^{-6}}
Cancel out 5 in both numerator and denominator.
\frac{125\times 1^{-2}\times \frac{1}{10}}{4^{-3}t^{-6}}
Multiply 5 and 25 to get 125.
\frac{125\times 1\times \frac{1}{10}}{4^{-3}t^{-6}}
Calculate 1 to the power of -2 and get 1.
\frac{125\times \frac{1}{10}}{4^{-3}t^{-6}}
Multiply 125 and 1 to get 125.
\frac{\frac{25}{2}}{4^{-3}t^{-6}}
Multiply 125 and \frac{1}{10} to get \frac{25}{2}.
\frac{\frac{25}{2}}{\frac{1}{64}t^{-6}}
Calculate 4 to the power of -3 and get \frac{1}{64}.
\frac{25}{2\times \frac{1}{64}t^{-6}}
Express \frac{\frac{25}{2}}{\frac{1}{64}t^{-6}} as a single fraction.
\frac{25}{\frac{1}{32}t^{-6}}
Multiply 2 and \frac{1}{64} to get \frac{1}{32}.