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Differentiate w.r.t. x
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\frac{1}{\left(x-8\right)\left(x-2\right)}+\frac{3}{\left(x-2\right)\left(x+16\right)}
Factor x^{2}-10x+16. Factor x^{2}+14x-32.
\frac{x+16}{\left(x-8\right)\left(x-2\right)\left(x+16\right)}+\frac{3\left(x-8\right)}{\left(x-8\right)\left(x-2\right)\left(x+16\right)}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of \left(x-8\right)\left(x-2\right) and \left(x-2\right)\left(x+16\right) is \left(x-8\right)\left(x-2\right)\left(x+16\right). Multiply \frac{1}{\left(x-8\right)\left(x-2\right)} times \frac{x+16}{x+16}. Multiply \frac{3}{\left(x-2\right)\left(x+16\right)} times \frac{x-8}{x-8}.
\frac{x+16+3\left(x-8\right)}{\left(x-8\right)\left(x-2\right)\left(x+16\right)}
Since \frac{x+16}{\left(x-8\right)\left(x-2\right)\left(x+16\right)} and \frac{3\left(x-8\right)}{\left(x-8\right)\left(x-2\right)\left(x+16\right)} have the same denominator, add them by adding their numerators.
\frac{x+16+3x-24}{\left(x-8\right)\left(x-2\right)\left(x+16\right)}
Do the multiplications in x+16+3\left(x-8\right).
\frac{4x-8}{\left(x-8\right)\left(x-2\right)\left(x+16\right)}
Combine like terms in x+16+3x-24.
\frac{4\left(x-2\right)}{\left(x-8\right)\left(x-2\right)\left(x+16\right)}
Factor the expressions that are not already factored in \frac{4x-8}{\left(x-8\right)\left(x-2\right)\left(x+16\right)}.
\frac{4}{\left(x-8\right)\left(x+16\right)}
Cancel out x-2 in both numerator and denominator.
\frac{4}{x^{2}+8x-128}
Expand \left(x-8\right)\left(x+16\right).