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Differentiate w.r.t. x
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\frac{1}{\left(x-1\right)\left(x+4\right)}-\frac{1}{\left(x-2\right)\left(x-1\right)}
Factor x^{2}+3x-4. Factor x^{2}-3x+2.
\frac{x-2}{\left(x-2\right)\left(x-1\right)\left(x+4\right)}-\frac{x+4}{\left(x-2\right)\left(x-1\right)\left(x+4\right)}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of \left(x-1\right)\left(x+4\right) and \left(x-2\right)\left(x-1\right) is \left(x-2\right)\left(x-1\right)\left(x+4\right). Multiply \frac{1}{\left(x-1\right)\left(x+4\right)} times \frac{x-2}{x-2}. Multiply \frac{1}{\left(x-2\right)\left(x-1\right)} times \frac{x+4}{x+4}.
\frac{x-2-\left(x+4\right)}{\left(x-2\right)\left(x-1\right)\left(x+4\right)}
Since \frac{x-2}{\left(x-2\right)\left(x-1\right)\left(x+4\right)} and \frac{x+4}{\left(x-2\right)\left(x-1\right)\left(x+4\right)} have the same denominator, subtract them by subtracting their numerators.
\frac{x-2-x-4}{\left(x-2\right)\left(x-1\right)\left(x+4\right)}
Do the multiplications in x-2-\left(x+4\right).
\frac{-6}{\left(x-2\right)\left(x-1\right)\left(x+4\right)}
Combine like terms in x-2-x-4.
\frac{-6}{x^{3}+x^{2}-10x+8}
Expand \left(x-2\right)\left(x-1\right)\left(x+4\right).