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Differentiate w.r.t. x
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\frac{x+4}{\left(x+4\right)\left(x+5\right)}-\frac{x+5}{\left(x+4\right)\left(x+5\right)}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of x+5 and x+4 is \left(x+4\right)\left(x+5\right). Multiply \frac{1}{x+5} times \frac{x+4}{x+4}. Multiply \frac{1}{x+4} times \frac{x+5}{x+5}.
\frac{x+4-\left(x+5\right)}{\left(x+4\right)\left(x+5\right)}
Since \frac{x+4}{\left(x+4\right)\left(x+5\right)} and \frac{x+5}{\left(x+4\right)\left(x+5\right)} have the same denominator, subtract them by subtracting their numerators.
\frac{x+4-x-5}{\left(x+4\right)\left(x+5\right)}
Do the multiplications in x+4-\left(x+5\right).
\frac{-1}{\left(x+4\right)\left(x+5\right)}
Combine like terms in x+4-x-5.
\frac{-1}{x^{2}+9x+20}
Expand \left(x+4\right)\left(x+5\right).