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Differentiate w.r.t. x
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\frac{x+3}{\left(x+3\right)\left(x+4\right)}-\frac{x+4}{\left(x+3\right)\left(x+4\right)}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of x+4 and x+3 is \left(x+3\right)\left(x+4\right). Multiply \frac{1}{x+4} times \frac{x+3}{x+3}. Multiply \frac{1}{x+3} times \frac{x+4}{x+4}.
\frac{x+3-\left(x+4\right)}{\left(x+3\right)\left(x+4\right)}
Since \frac{x+3}{\left(x+3\right)\left(x+4\right)} and \frac{x+4}{\left(x+3\right)\left(x+4\right)} have the same denominator, subtract them by subtracting their numerators.
\frac{x+3-x-4}{\left(x+3\right)\left(x+4\right)}
Do the multiplications in x+3-\left(x+4\right).
\frac{-1}{\left(x+3\right)\left(x+4\right)}
Combine like terms in x+3-x-4.
\frac{-1}{x^{2}+7x+12}
Expand \left(x+3\right)\left(x+4\right).