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\frac{\left(-x-4\right)\left(3x^{2}-24x+48\right)}{\left(x^{2}-4x\right)\left(x+4\right)}
Multiply \frac{-x-4}{x^{2}-4x} times \frac{3x^{2}-24x+48}{x+4} by multiplying numerator times numerator and denominator times denominator.
\frac{3\left(-x-4\right)\left(x-4\right)^{2}}{x\left(x-4\right)\left(x+4\right)}
Factor the expressions that are not already factored.
\frac{-3\left(x+4\right)\left(x-4\right)^{2}}{x\left(x-4\right)\left(x+4\right)}
Extract the negative sign in -4-x.
\frac{-3\left(x-4\right)}{x}
Cancel out \left(x-4\right)\left(x+4\right) in both numerator and denominator.
\frac{-3x+12}{x}
Expand the expression.
\frac{\left(-x-4\right)\left(3x^{2}-24x+48\right)}{\left(x^{2}-4x\right)\left(x+4\right)}
Multiply \frac{-x-4}{x^{2}-4x} times \frac{3x^{2}-24x+48}{x+4} by multiplying numerator times numerator and denominator times denominator.
\frac{3\left(-x-4\right)\left(x-4\right)^{2}}{x\left(x-4\right)\left(x+4\right)}
Factor the expressions that are not already factored.
\frac{-3\left(x+4\right)\left(x-4\right)^{2}}{x\left(x-4\right)\left(x+4\right)}
Extract the negative sign in -4-x.
\frac{-3\left(x-4\right)}{x}
Cancel out \left(x-4\right)\left(x+4\right) in both numerator and denominator.
\frac{-3x+12}{x}
Expand the expression.