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Differentiate w.r.t. a
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\frac{\left(-a^{2}\right)a}{-a^{8}}
Express \frac{-a^{2}}{-a^{8}}a as a single fraction.
\frac{-a^{2}}{-a^{7}}
Cancel out a in both numerator and denominator.
\frac{1}{a^{5}}
Cancel out -a^{2} in both numerator and denominator.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{\left(-a^{2}\right)a}{-a^{8}})
Express \frac{-a^{2}}{-a^{8}}a as a single fraction.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{-a^{2}}{-a^{7}})
Cancel out a in both numerator and denominator.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{1}{a^{5}})
Cancel out -a^{2} in both numerator and denominator.
-\left(a^{5}\right)^{-1-1}\frac{\mathrm{d}}{\mathrm{d}a}(a^{5})
If F is the composition of two differentiable functions f\left(u\right) and u=g\left(x\right), that is, if F\left(x\right)=f\left(g\left(x\right)\right), then the derivative of F is the derivative of f with respect to u times the derivative of g with respect to x, that is, \frac{\mathrm{d}}{\mathrm{d}x}(F)\left(x\right)=\frac{\mathrm{d}}{\mathrm{d}x}(f)\left(g\left(x\right)\right)\frac{\mathrm{d}}{\mathrm{d}x}(g)\left(x\right).
-\left(a^{5}\right)^{-2}\times 5a^{5-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-5a^{4}\left(a^{5}\right)^{-2}
Simplify.