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Evaluate
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Differentiate w.r.t. x
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\frac{-8}{9x^{2}}\times \frac{81x^{8}}{64x}
Cancel out x^{4} in both numerator and denominator.
\frac{-8}{9x^{2}}\times \frac{81x^{7}}{64}
Cancel out x in both numerator and denominator.
\frac{-8\times 81x^{7}}{9x^{2}\times 64}
Multiply \frac{-8}{9x^{2}} times \frac{81x^{7}}{64} by multiplying numerator times numerator and denominator times denominator.
\frac{-9x^{5}}{8}
Cancel out 8\times 9x^{2} in both numerator and denominator.