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Differentiate w.r.t. x
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\frac{-5\left(-x^{5}\right)}{x^{3}\times 3}\times \frac{-4}{x}\times \frac{20}{x^{3}}
Multiply \frac{-5}{x^{3}} times \frac{-x^{5}}{3} by multiplying numerator times numerator and denominator times denominator.
\frac{-5\left(-x^{5}\right)\left(-4\right)}{x^{3}\times 3x}\times \frac{20}{x^{3}}
Multiply \frac{-5\left(-x^{5}\right)}{x^{3}\times 3} times \frac{-4}{x} by multiplying numerator times numerator and denominator times denominator.
\frac{-5\left(-x^{5}\right)\left(-4\right)\times 20}{x^{3}\times 3xx^{3}}
Multiply \frac{-5\left(-x^{5}\right)\left(-4\right)}{x^{3}\times 3x} times \frac{20}{x^{3}} by multiplying numerator times numerator and denominator times denominator.
\frac{-5\left(-x^{5}\right)\left(-4\right)\times 20}{x^{4}\times 3x^{3}}
To multiply powers of the same base, add their exponents. Add 3 and 1 to get 4.
\frac{-5\left(-x^{5}\right)\left(-4\right)\times 20}{x^{7}\times 3}
To multiply powers of the same base, add their exponents. Add 4 and 3 to get 7.
\frac{20\left(-x^{5}\right)\times 20}{x^{7}\times 3}
Multiply -5 and -4 to get 20.
\frac{400\left(-x^{5}\right)}{x^{7}\times 3}
Multiply 20 and 20 to get 400.
\frac{-400x^{5}}{3x^{7}}
Factor the expressions that are not already factored.
\frac{-400}{3x^{2}}
Cancel out x^{5} in both numerator and denominator.