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\frac{\left(-42x^{2}-180x\right)\times 3}{\left(100-x^{2}\right)\times 4x}\times \frac{-x-6}{x^{2}-3x-18}
Multiply \frac{-42x^{2}-180x}{100-x^{2}} times \frac{3}{4x} by multiplying numerator times numerator and denominator times denominator.
\frac{\left(-42x^{2}-180x\right)\times 3\left(-x-6\right)}{\left(100-x^{2}\right)\times 4x\left(x^{2}-3x-18\right)}
Multiply \frac{\left(-42x^{2}-180x\right)\times 3}{\left(100-x^{2}\right)\times 4x} times \frac{-x-6}{x^{2}-3x-18} by multiplying numerator times numerator and denominator times denominator.
\frac{3\times 6x\left(-7x-30\right)\left(-x-6\right)}{4x\left(x-10\right)\left(x-6\right)\left(-x-10\right)\left(x+3\right)}
Factor the expressions that are not already factored.
\frac{3\times 3\left(-7x-30\right)\left(-x-6\right)}{2\left(x-10\right)\left(x-6\right)\left(-x-10\right)\left(x+3\right)}
Cancel out 2x in both numerator and denominator.
\frac{63x^{2}+648x+1620}{-2x^{4}+6x^{3}+236x^{2}-600x-3600}
Expand the expression.
\frac{\left(-42x^{2}-180x\right)\times 3}{\left(100-x^{2}\right)\times 4x}\times \frac{-x-6}{x^{2}-3x-18}
Multiply \frac{-42x^{2}-180x}{100-x^{2}} times \frac{3}{4x} by multiplying numerator times numerator and denominator times denominator.
\frac{\left(-42x^{2}-180x\right)\times 3\left(-x-6\right)}{\left(100-x^{2}\right)\times 4x\left(x^{2}-3x-18\right)}
Multiply \frac{\left(-42x^{2}-180x\right)\times 3}{\left(100-x^{2}\right)\times 4x} times \frac{-x-6}{x^{2}-3x-18} by multiplying numerator times numerator and denominator times denominator.
\frac{3\times 6x\left(-7x-30\right)\left(-x-6\right)}{4x\left(x-10\right)\left(x-6\right)\left(-x-10\right)\left(x+3\right)}
Factor the expressions that are not already factored.
\frac{3\times 3\left(-7x-30\right)\left(-x-6\right)}{2\left(x-10\right)\left(x-6\right)\left(-x-10\right)\left(x+3\right)}
Cancel out 2x in both numerator and denominator.
\frac{63x^{2}+648x+1620}{-2x^{4}+6x^{3}+236x^{2}-600x-3600}
Expand the expression.