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Differentiate w.r.t. d
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\frac{-4a^{2}b^{6}}{c^{2}}\times \frac{8b^{6}d^{-6}}{a^{-15}e^{9}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{-4a^{2}b^{6}\times 8b^{6}d^{-6}}{c^{2}a^{-15}e^{9}}
Multiply \frac{-4a^{2}b^{6}}{c^{2}} times \frac{8b^{6}d^{-6}}{a^{-15}e^{9}} by multiplying numerator times numerator and denominator times denominator.
\frac{-4\times 8d^{-6}b^{6}b^{6}a^{17}}{e^{9}c^{2}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{-4\times 8d^{-6}b^{12}a^{17}}{e^{9}c^{2}}
To multiply powers of the same base, add their exponents. Add 6 and 6 to get 12.
\frac{-32d^{-6}b^{12}a^{17}}{e^{9}c^{2}}
Multiply -4 and 8 to get -32.