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\frac{-1099511627776}{28^{3}\left(-45^{2}\right)}
Calculate 32 to the power of 8 and get 1099511627776.
\frac{-1099511627776}{21952\left(-45^{2}\right)}
Calculate 28 to the power of 3 and get 21952.
\frac{-1099511627776}{21952\left(-2025\right)}
Calculate 45 to the power of 2 and get 2025.
\frac{-1099511627776}{-44452800}
Multiply 21952 and -2025 to get -44452800.
\frac{17179869184}{694575}
Reduce the fraction \frac{-1099511627776}{-44452800} to lowest terms by extracting and canceling out -64.