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Evaluate
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Differentiate w.r.t. x
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\frac{-5x^{6}}{-4x^{-3}z^{2}}
Cancel out 2y^{-2}z^{3} in both numerator and denominator.
\frac{-5x^{9}}{-4z^{2}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\left(-\frac{\frac{10z^{3}}{y^{2}}}{-\frac{8z^{5}}{y^{2}}}\right)x^{6-\left(-3\right)})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{5}{4z^{2}}x^{9})
Do the arithmetic.
9\times \frac{5}{4z^{2}}x^{9-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\frac{45}{4z^{2}}x^{8}
Do the arithmetic.