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\frac{\left(-4^{2}\left(a^{3}\right)^{2}b^{2}\right)\times 3a^{5}}{8b^{4}}
Expand \left(4a^{3}b\right)^{2}.
\frac{\left(-4^{2}a^{6}b^{2}\right)\times 3a^{5}}{8b^{4}}
To raise a power to another power, multiply the exponents. Multiply 3 and 2 to get 6.
\frac{\left(-16a^{6}b^{2}\right)\times 3a^{5}}{8b^{4}}
Calculate 4 to the power of 2 and get 16.
\frac{-3\times 16b^{2}a^{5}a^{6}}{8b^{4}}
Factor the expressions that are not already factored.
\frac{-2\times 3a^{5}a^{6}}{b^{2}}
Cancel out 8b^{2} in both numerator and denominator.
\frac{-6a^{11}}{b^{2}}
Expand the expression.
\frac{\left(-4^{2}\left(a^{3}\right)^{2}b^{2}\right)\times 3a^{5}}{8b^{4}}
Expand \left(4a^{3}b\right)^{2}.
\frac{\left(-4^{2}a^{6}b^{2}\right)\times 3a^{5}}{8b^{4}}
To raise a power to another power, multiply the exponents. Multiply 3 and 2 to get 6.
\frac{\left(-16a^{6}b^{2}\right)\times 3a^{5}}{8b^{4}}
Calculate 4 to the power of 2 and get 16.
\frac{-3\times 16b^{2}a^{5}a^{6}}{8b^{4}}
Factor the expressions that are not already factored.
\frac{-2\times 3a^{5}a^{6}}{b^{2}}
Cancel out 8b^{2} in both numerator and denominator.
\frac{-6a^{11}}{b^{2}}
Expand the expression.