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Differentiate w.r.t. x
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\frac{\left(x^{3}\right)^{2}\left(y^{2}\right)^{2}}{\left(x^{-1}y^{-\frac{2}{3}}\right)^{\frac{1}{4}}}
Expand \left(x^{3}y^{2}\right)^{2}.
\frac{x^{6}\left(y^{2}\right)^{2}}{\left(x^{-1}y^{-\frac{2}{3}}\right)^{\frac{1}{4}}}
To raise a power to another power, multiply the exponents. Multiply 3 and 2 to get 6.
\frac{x^{6}y^{4}}{\left(x^{-1}y^{-\frac{2}{3}}\right)^{\frac{1}{4}}}
To raise a power to another power, multiply the exponents. Multiply 2 and 2 to get 4.
\frac{x^{6}y^{4}}{\left(x^{-1}\right)^{\frac{1}{4}}\left(y^{-\frac{2}{3}}\right)^{\frac{1}{4}}}
Expand \left(x^{-1}y^{-\frac{2}{3}}\right)^{\frac{1}{4}}.
\frac{x^{6}y^{4}}{x^{-\frac{1}{4}}\left(y^{-\frac{2}{3}}\right)^{\frac{1}{4}}}
To raise a power to another power, multiply the exponents. Multiply -1 and \frac{1}{4} to get -\frac{1}{4}.
\frac{x^{6}y^{4}}{x^{-\frac{1}{4}}y^{-\frac{1}{6}}}
To raise a power to another power, multiply the exponents. Multiply -\frac{2}{3} and \frac{1}{4} to get -\frac{1}{6}.
y^{\frac{25}{6}}x^{\frac{25}{4}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.