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Differentiate w.r.t. x
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\frac{\left(x^{-2}\right)^{2^{4}}\left(\left(-x^{-2}\right)^{3^{2^{2}}}\right)^{-1}}{x^{2^{3}}\left(\left(-x^{3}\right)^{3^{2}}\right)^{2^{3}}}
Calculate 2 to the power of 2 and get 4.
\frac{\left(x^{-2}\right)^{16}\left(\left(-x^{-2}\right)^{3^{2^{2}}}\right)^{-1}}{x^{2^{3}}\left(\left(-x^{3}\right)^{3^{2}}\right)^{2^{3}}}
Calculate 2 to the power of 4 and get 16.
\frac{\left(x^{-2}\right)^{16}\left(\left(-x^{-2}\right)^{3^{4}}\right)^{-1}}{x^{2^{3}}\left(\left(-x^{3}\right)^{3^{2}}\right)^{2^{3}}}
Calculate 2 to the power of 2 and get 4.
\frac{\left(x^{-2}\right)^{16}\left(\left(-x^{-2}\right)^{81}\right)^{-1}}{x^{2^{3}}\left(\left(-x^{3}\right)^{3^{2}}\right)^{2^{3}}}
Calculate 3 to the power of 4 and get 81.
\frac{\left(x^{-2}\right)^{16}\left(\left(-x^{-2}\right)^{81}\right)^{-1}}{x^{8}\left(\left(-x^{3}\right)^{3^{2}}\right)^{2^{3}}}
Calculate 2 to the power of 3 and get 8.
\frac{\left(x^{-2}\right)^{16}\left(\left(-x^{-2}\right)^{81}\right)^{-1}}{x^{8}\left(\left(-x^{3}\right)^{9}\right)^{2^{3}}}
Calculate 3 to the power of 2 and get 9.
\frac{\left(x^{-2}\right)^{16}\left(\left(-x^{-2}\right)^{81}\right)^{-1}}{x^{8}\left(\left(-x^{3}\right)^{9}\right)^{8}}
Calculate 2 to the power of 3 and get 8.
\frac{x^{-32}\left(\left(-x^{-2}\right)^{81}\right)^{-1}}{x^{8}\left(\left(-x^{3}\right)^{9}\right)^{8}}
To raise a power to another power, multiply the exponents. Multiply -2 and 16 to get -32.
\frac{x^{-32}\left(-x^{-2}\right)^{-81}}{x^{8}\left(\left(-x^{3}\right)^{9}\right)^{8}}
To raise a power to another power, multiply the exponents. Multiply 81 and -1 to get -81.
\frac{x^{-32}\left(-x^{-2}\right)^{-81}}{x^{8}\left(-x^{3}\right)^{72}}
To raise a power to another power, multiply the exponents. Multiply 9 and 8 to get 72.
\frac{\left(-x^{-2}\right)^{-81}}{x^{40}\left(-x^{3}\right)^{72}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{\left(-1\right)^{-81}\left(x^{-2}\right)^{-81}}{x^{40}\left(-x^{3}\right)^{72}}
Expand \left(-x^{-2}\right)^{-81}.
\frac{\left(-1\right)^{-81}x^{162}}{x^{40}\left(-x^{3}\right)^{72}}
To raise a power to another power, multiply the exponents. Multiply -2 and -81 to get 162.
\frac{-x^{162}}{x^{40}\left(-x^{3}\right)^{72}}
Calculate -1 to the power of -81 and get -1.
\frac{-x^{162}}{x^{40}\left(-1\right)^{72}\left(x^{3}\right)^{72}}
Expand \left(-x^{3}\right)^{72}.
\frac{-x^{162}}{x^{40}\left(-1\right)^{72}x^{216}}
To raise a power to another power, multiply the exponents. Multiply 3 and 72 to get 216.
\frac{-x^{162}}{x^{40}\times 1x^{216}}
Calculate -1 to the power of 72 and get 1.
\frac{-x^{162}}{x^{256}\times 1}
To multiply powers of the same base, add their exponents. Add 40 and 216 to get 256.
\frac{-1}{x^{94}}
Cancel out x^{162} in both numerator and denominator.