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Differentiate w.r.t. a
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\frac{u^{12}\left(a^{5}\right)^{2}}{\left(u^{3}\right)^{4}\left(u^{2}\right)^{3}}
To raise a power to another power, multiply the exponents. Multiply 4 and 3 to get 12.
\frac{u^{12}a^{10}}{\left(u^{3}\right)^{4}\left(u^{2}\right)^{3}}
To raise a power to another power, multiply the exponents. Multiply 5 and 2 to get 10.
\frac{u^{12}a^{10}}{u^{12}\left(u^{2}\right)^{3}}
To raise a power to another power, multiply the exponents. Multiply 3 and 4 to get 12.
\frac{u^{12}a^{10}}{u^{12}u^{6}}
To raise a power to another power, multiply the exponents. Multiply 2 and 3 to get 6.
\frac{u^{12}a^{10}}{u^{18}}
To multiply powers of the same base, add their exponents. Add 12 and 6 to get 18.
\frac{a^{10}}{u^{6}}
Cancel out u^{12} in both numerator and denominator.