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Differentiate w.r.t. a
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\frac{a^{10}}{\left(a^{3}\right)^{4}}
To raise a power to another power, multiply the exponents. Multiply 5 and 2 to get 10.
\frac{a^{10}}{a^{12}}
To raise a power to another power, multiply the exponents. Multiply 3 and 4 to get 12.
\frac{1}{a^{2}}
Rewrite a^{12} as a^{10}a^{2}. Cancel out a^{10} in both numerator and denominator.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{a^{10}}{\left(a^{3}\right)^{4}})
To raise a power to another power, multiply the exponents. Multiply 5 and 2 to get 10.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{a^{10}}{a^{12}})
To raise a power to another power, multiply the exponents. Multiply 3 and 4 to get 12.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{1}{a^{2}})
Rewrite a^{12} as a^{10}a^{2}. Cancel out a^{10} in both numerator and denominator.
-\left(a^{2}\right)^{-1-1}\frac{\mathrm{d}}{\mathrm{d}a}(a^{2})
If F is the composition of two differentiable functions f\left(u\right) and u=g\left(x\right), that is, if F\left(x\right)=f\left(g\left(x\right)\right), then the derivative of F is the derivative of f with respect to u times the derivative of g with respect to x, that is, \frac{\mathrm{d}}{\mathrm{d}x}(F)\left(x\right)=\frac{\mathrm{d}}{\mathrm{d}x}(f)\left(g\left(x\right)\right)\frac{\mathrm{d}}{\mathrm{d}x}(g)\left(x\right).
-\left(a^{2}\right)^{-2}\times 2a^{2-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-2a^{1}\left(a^{2}\right)^{-2}
Simplify.
-2a\left(a^{2}\right)^{-2}
For any term t, t^{1}=t.