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Differentiate w.r.t. a
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\frac{\frac{a^{6}a^{-2}}{a^{4}}}{a^{2}a^{3}}
To raise a power to another power, multiply the exponents. Multiply 3 and 2 to get 6.
\frac{\frac{a^{4}}{a^{4}}}{a^{2}a^{3}}
To multiply powers of the same base, add their exponents. Add 6 and -2 to get 4.
\frac{1}{a^{2}a^{3}}
Divide a^{4} by a^{4} to get 1.
\frac{1}{a^{5}}
To multiply powers of the same base, add their exponents. Add 2 and 3 to get 5.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{\frac{a^{6}a^{-2}}{a^{4}}}{a^{2}a^{3}})
To raise a power to another power, multiply the exponents. Multiply 3 and 2 to get 6.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{\frac{a^{4}}{a^{4}}}{a^{2}a^{3}})
To multiply powers of the same base, add their exponents. Add 6 and -2 to get 4.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{1}{a^{2}a^{3}})
Divide a^{4} by a^{4} to get 1.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{1}{a^{5}})
To multiply powers of the same base, add their exponents. Add 2 and 3 to get 5.
-\left(a^{5}\right)^{-1-1}\frac{\mathrm{d}}{\mathrm{d}a}(a^{5})
If F is the composition of two differentiable functions f\left(u\right) and u=g\left(x\right), that is, if F\left(x\right)=f\left(g\left(x\right)\right), then the derivative of F is the derivative of f with respect to u times the derivative of g with respect to x, that is, \frac{\mathrm{d}}{\mathrm{d}x}(F)\left(x\right)=\frac{\mathrm{d}}{\mathrm{d}x}(f)\left(g\left(x\right)\right)\frac{\mathrm{d}}{\mathrm{d}x}(g)\left(x\right).
-\left(a^{5}\right)^{-2}\times 5a^{5-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-5a^{4}\left(a^{5}\right)^{-2}
Simplify.