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\frac{5^{-6}\times 10}{\left(3^{-2}\right)^{-3}\times \left(5^{4}\right)^{-2}}
To raise a power to another power, multiply the exponents. Multiply -3 and 2 to get -6.
\frac{5^{-6}\times 10}{3^{6}\times \left(5^{4}\right)^{-2}}
To raise a power to another power, multiply the exponents. Multiply -2 and -3 to get 6.
\frac{5^{-6}\times 10}{3^{6}\times 5^{-8}}
To raise a power to another power, multiply the exponents. Multiply 4 and -2 to get -8.
\frac{10\times 5^{2}}{3^{6}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{10\times 25}{3^{6}}
Calculate 5 to the power of 2 and get 25.
\frac{250}{3^{6}}
Multiply 10 and 25 to get 250.
\frac{250}{729}
Calculate 3 to the power of 6 and get 729.