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\frac{1.5\left(4.5-4\right)\left(4.5-5\right)\left(4.5-6\right)\left(-6\right)\times 4.5^{-4}}{4!}
Subtract 3 from 4.5 to get 1.5.
\frac{1.5\times 0.5\left(4.5-5\right)\left(4.5-6\right)\left(-6\right)\times 4.5^{-4}}{4!}
Subtract 4 from 4.5 to get 0.5.
\frac{0.75\left(4.5-5\right)\left(4.5-6\right)\left(-6\right)\times 4.5^{-4}}{4!}
Multiply 1.5 and 0.5 to get 0.75.
\frac{0.75\left(-0.5\right)\left(4.5-6\right)\left(-6\right)\times 4.5^{-4}}{4!}
Subtract 5 from 4.5 to get -0.5.
\frac{-0.375\left(4.5-6\right)\left(-6\right)\times 4.5^{-4}}{4!}
Multiply 0.75 and -0.5 to get -0.375.
\frac{-0.375\left(-1.5\right)\left(-6\right)\times 4.5^{-4}}{4!}
Subtract 6 from 4.5 to get -1.5.
\frac{0.5625\left(-6\right)\times 4.5^{-4}}{4!}
Multiply -0.375 and -1.5 to get 0.5625.
\frac{-3.375\times 4.5^{-4}}{4!}
Multiply 0.5625 and -6 to get -3.375.
\frac{-3.375\times \frac{16}{6561}}{4!}
Calculate 4.5 to the power of -4 and get \frac{16}{6561}.
\frac{-\frac{2}{243}}{4!}
Multiply -3.375 and \frac{16}{6561} to get -\frac{2}{243}.
\frac{-\frac{2}{243}}{24}
The factorial of 4 is 24.