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\frac{4^{2}\left(x^{3}\right)^{2}}{\left(-2x^{5}\right)^{3}}
Expand \left(4x^{3}\right)^{2}.
\frac{4^{2}x^{6}}{\left(-2x^{5}\right)^{3}}
To raise a power to another power, multiply the exponents. Multiply 3 and 2 to get 6.
\frac{16x^{6}}{\left(-2x^{5}\right)^{3}}
Calculate 4 to the power of 2 and get 16.
\frac{16x^{6}}{\left(-2\right)^{3}\left(x^{5}\right)^{3}}
Expand \left(-2x^{5}\right)^{3}.
\frac{16x^{6}}{\left(-2\right)^{3}x^{15}}
To raise a power to another power, multiply the exponents. Multiply 5 and 3 to get 15.
\frac{16x^{6}}{-8x^{15}}
Calculate -2 to the power of 3 and get -8.
\frac{2}{-x^{9}}
Cancel out 8x^{6} in both numerator and denominator.
\frac{4^{2}\left(x^{3}\right)^{2}}{\left(-2x^{5}\right)^{3}}
Expand \left(4x^{3}\right)^{2}.
\frac{4^{2}x^{6}}{\left(-2x^{5}\right)^{3}}
To raise a power to another power, multiply the exponents. Multiply 3 and 2 to get 6.
\frac{16x^{6}}{\left(-2x^{5}\right)^{3}}
Calculate 4 to the power of 2 and get 16.
\frac{16x^{6}}{\left(-2\right)^{3}\left(x^{5}\right)^{3}}
Expand \left(-2x^{5}\right)^{3}.
\frac{16x^{6}}{\left(-2\right)^{3}x^{15}}
To raise a power to another power, multiply the exponents. Multiply 5 and 3 to get 15.
\frac{16x^{6}}{-8x^{15}}
Calculate -2 to the power of 3 and get -8.
\frac{2}{-x^{9}}
Cancel out 8x^{6} in both numerator and denominator.