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Differentiate w.r.t. x
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\frac{32x^{-2}b^{8}\left(-5\right)b}{-4x^{3}b\left(-2\right)x^{2}b^{2}\times 5x^{3}b}
To multiply powers of the same base, add their exponents. Add 2 and -4 to get -2.
\frac{32x^{-2}b^{9}\left(-5\right)}{-4x^{3}b\left(-2\right)x^{2}b^{2}\times 5x^{3}b}
To multiply powers of the same base, add their exponents. Add 8 and 1 to get 9.
\frac{32x^{-2}b^{9}\left(-5\right)}{-4x^{5}b\left(-2\right)b^{2}\times 5x^{3}b}
To multiply powers of the same base, add their exponents. Add 3 and 2 to get 5.
\frac{32x^{-2}b^{9}\left(-5\right)}{-4x^{8}b\left(-2\right)b^{2}\times 5b}
To multiply powers of the same base, add their exponents. Add 5 and 3 to get 8.
\frac{32x^{-2}b^{9}\left(-5\right)}{-4x^{8}b^{3}\left(-2\right)\times 5b}
To multiply powers of the same base, add their exponents. Add 1 and 2 to get 3.
\frac{32x^{-2}b^{9}\left(-5\right)}{-4x^{8}b^{4}\left(-2\right)\times 5}
To multiply powers of the same base, add their exponents. Add 3 and 1 to get 4.
\frac{-4x^{-2}b^{5}}{-\left(-1\right)x^{8}}
Cancel out 2\times 4\times 5b^{4} in both numerator and denominator.
\frac{4x^{-2}b^{5}}{-x^{8}}
Cancel out -1 in both numerator and denominator.
\frac{4b^{5}}{-x^{10}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{-4b^{5}}{x^{10}}
Cancel out -1 in both numerator and denominator.
\frac{\mathrm{d}}{\mathrm{d}x}(\left(-\frac{\frac{160b^{9}}{x^{4}}}{40b^{4}x^{5}}\right)x^{2-3})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\left(-\frac{4b^{5}}{x^{9}}\right)\times \frac{1}{x})
Do the arithmetic.
-\left(-\frac{4b^{5}}{x^{9}}\right)x^{-1-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\frac{4b^{5}}{x^{9}}x^{-2}
Do the arithmetic.