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Differentiate w.r.t. c
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\frac{2^{-3}c^{-3}\left(a^{-5}\right)^{-3}\left(b^{4}\right)^{-3}\left(ab\right)^{-1}}{\left(3a^{3}\right)^{2}\times \left(4b^{-9}c\right)^{0}}
Expand \left(2ca^{-5}b^{4}\right)^{-3}.
\frac{2^{-3}c^{-3}a^{15}\left(b^{4}\right)^{-3}\left(ab\right)^{-1}}{\left(3a^{3}\right)^{2}\times \left(4b^{-9}c\right)^{0}}
To raise a power to another power, multiply the exponents. Multiply -5 and -3 to get 15.
\frac{2^{-3}c^{-3}a^{15}b^{-12}\left(ab\right)^{-1}}{\left(3a^{3}\right)^{2}\times \left(4b^{-9}c\right)^{0}}
To raise a power to another power, multiply the exponents. Multiply 4 and -3 to get -12.
\frac{\frac{1}{8}c^{-3}a^{15}b^{-12}\left(ab\right)^{-1}}{\left(3a^{3}\right)^{2}\times \left(4b^{-9}c\right)^{0}}
Calculate 2 to the power of -3 and get \frac{1}{8}.
\frac{\frac{1}{8}c^{-3}a^{15}b^{-12}a^{-1}b^{-1}}{\left(3a^{3}\right)^{2}\times \left(4b^{-9}c\right)^{0}}
Expand \left(ab\right)^{-1}.
\frac{\frac{1}{8}c^{-3}a^{14}b^{-12}b^{-1}}{\left(3a^{3}\right)^{2}\times \left(4b^{-9}c\right)^{0}}
To multiply powers of the same base, add their exponents. Add 15 and -1 to get 14.
\frac{\frac{1}{8}c^{-3}a^{14}b^{-13}}{\left(3a^{3}\right)^{2}\times \left(4b^{-9}c\right)^{0}}
To multiply powers of the same base, add their exponents. Add -12 and -1 to get -13.
\frac{\frac{1}{8}c^{-3}a^{14}b^{-13}}{3^{2}\left(a^{3}\right)^{2}\times \left(4b^{-9}c\right)^{0}}
Expand \left(3a^{3}\right)^{2}.
\frac{\frac{1}{8}c^{-3}a^{14}b^{-13}}{3^{2}a^{6}\times \left(4b^{-9}c\right)^{0}}
To raise a power to another power, multiply the exponents. Multiply 3 and 2 to get 6.
\frac{\frac{1}{8}c^{-3}a^{14}b^{-13}}{9a^{6}\times \left(4b^{-9}c\right)^{0}}
Calculate 3 to the power of 2 and get 9.
\frac{\frac{1}{8}c^{-3}a^{14}b^{-13}}{9a^{6}\times 1}
Calculate 4b^{-9}c to the power of 0 and get 1.
\frac{\frac{1}{8}c^{-3}a^{14}b^{-13}}{9a^{6}}
Multiply 9 and 1 to get 9.
\frac{\frac{1}{8}b^{-13}c^{-3}a^{8}}{9}
Cancel out a^{6} in both numerator and denominator.
\frac{1}{72}b^{-13}c^{-3}a^{8}
Divide \frac{1}{8}b^{-13}c^{-3}a^{8} by 9 to get \frac{1}{72}b^{-13}c^{-3}a^{8}.