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\frac{4\left(-3\right)^{5}\times 2^{4}}{9\left(-2^{7}\right)\left(-9\right)^{2}}
Cancel out 2 in both numerator and denominator.
\frac{4\left(-243\right)\times 2^{4}}{9\left(-2^{7}\right)\left(-9\right)^{2}}
Calculate -3 to the power of 5 and get -243.
\frac{-972\times 2^{4}}{9\left(-2^{7}\right)\left(-9\right)^{2}}
Multiply 4 and -243 to get -972.
\frac{-972\times 16}{9\left(-2^{7}\right)\left(-9\right)^{2}}
Calculate 2 to the power of 4 and get 16.
\frac{-15552}{9\left(-2^{7}\right)\left(-9\right)^{2}}
Multiply -972 and 16 to get -15552.
\frac{-15552}{9\left(-128\right)\left(-9\right)^{2}}
Calculate 2 to the power of 7 and get 128.
\frac{-15552}{-1152\left(-9\right)^{2}}
Multiply 9 and -128 to get -1152.
\frac{-15552}{-1152\times 81}
Calculate -9 to the power of 2 and get 81.
\frac{-15552}{-93312}
Multiply -1152 and 81 to get -93312.
\frac{1}{6}
Reduce the fraction \frac{-15552}{-93312} to lowest terms by extracting and canceling out -15552.