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\frac{\left(-2\right)^{5}x^{5}y^{5}}{\left(x^{2}y^{-1}\right)^{-2}}
Expand \left(-2xy\right)^{5}.
\frac{-32x^{5}y^{5}}{\left(x^{2}y^{-1}\right)^{-2}}
Calculate -2 to the power of 5 and get -32.
\frac{-32x^{5}y^{5}}{\left(x^{2}\right)^{-2}\left(y^{-1}\right)^{-2}}
Expand \left(x^{2}y^{-1}\right)^{-2}.
\frac{-32x^{5}y^{5}}{x^{-4}\left(y^{-1}\right)^{-2}}
To raise a power to another power, multiply the exponents. Multiply 2 and -2 to get -4.
\frac{-32x^{5}y^{5}}{x^{-4}y^{2}}
To raise a power to another power, multiply the exponents. Multiply -1 and -2 to get 2.
\frac{-32y^{3}x^{5}}{x^{-4}}
Cancel out y^{2} in both numerator and denominator.
-32y^{3}x^{9}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\left(-2\right)^{5}x^{5}y^{5}}{\left(x^{2}y^{-1}\right)^{-2}}
Expand \left(-2xy\right)^{5}.
\frac{-32x^{5}y^{5}}{\left(x^{2}y^{-1}\right)^{-2}}
Calculate -2 to the power of 5 and get -32.
\frac{-32x^{5}y^{5}}{\left(x^{2}\right)^{-2}\left(y^{-1}\right)^{-2}}
Expand \left(x^{2}y^{-1}\right)^{-2}.
\frac{-32x^{5}y^{5}}{x^{-4}\left(y^{-1}\right)^{-2}}
To raise a power to another power, multiply the exponents. Multiply 2 and -2 to get -4.
\frac{-32x^{5}y^{5}}{x^{-4}y^{2}}
To raise a power to another power, multiply the exponents. Multiply -1 and -2 to get 2.
\frac{-32y^{3}x^{5}}{x^{-4}}
Cancel out y^{2} in both numerator and denominator.
-32y^{3}x^{9}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.