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Differentiate w.r.t. x
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\frac{36x^{4}\times 15z^{5}}{5y^{4}z^{5}\times 9xy^{2}}
Divide \frac{36x^{4}}{5y^{4}z^{5}} by \frac{9xy^{2}}{15z^{5}} by multiplying \frac{36x^{4}}{5y^{4}z^{5}} by the reciprocal of \frac{9xy^{2}}{15z^{5}}.
\frac{3\times 4x^{3}}{y^{2}y^{4}}
Cancel out 5\times 9xz^{5} in both numerator and denominator.
\frac{12x^{3}}{y^{2}y^{4}}
Multiply 3 and 4 to get 12.
\frac{12x^{3}}{y^{6}}
To multiply powers of the same base, add their exponents. Add 2 and 4 to get 6.