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\frac{3\left(2x-1\right)}{\left(2x-1\right)\left(x+3\right)}-\frac{6\left(x+3\right)}{\left(2x-1\right)\left(x+3\right)}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of x+3 and 2x-1 is \left(2x-1\right)\left(x+3\right). Multiply \frac{3}{x+3} times \frac{2x-1}{2x-1}. Multiply \frac{6}{2x-1} times \frac{x+3}{x+3}.
\frac{3\left(2x-1\right)-6\left(x+3\right)}{\left(2x-1\right)\left(x+3\right)}
Since \frac{3\left(2x-1\right)}{\left(2x-1\right)\left(x+3\right)} and \frac{6\left(x+3\right)}{\left(2x-1\right)\left(x+3\right)} have the same denominator, subtract them by subtracting their numerators.
\frac{6x-3-6x-18}{\left(2x-1\right)\left(x+3\right)}
Do the multiplications in 3\left(2x-1\right)-6\left(x+3\right).
\frac{-21}{\left(2x-1\right)\left(x+3\right)}
Combine like terms in 6x-3-6x-18.
\frac{-21}{2x^{2}+5x-3}
Expand \left(2x-1\right)\left(x+3\right).