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\left(1-3\right)^{2}\left(-4+6\right)^{5}\left(8-10\right)^{6}-2^{10}\left(-1+3\right)^{3}
Calculate 2 to the power of 0 and get 1.
\left(-2\right)^{2}\left(-4+6\right)^{5}\left(8-10\right)^{6}-2^{10}\left(-1+3\right)^{3}
Subtract 3 from 1 to get -2.
4\left(-4+6\right)^{5}\left(8-10\right)^{6}-2^{10}\left(-1+3\right)^{3}
Calculate -2 to the power of 2 and get 4.
4\times 2^{5}\left(8-10\right)^{6}-2^{10}\left(-1+3\right)^{3}
Add -4 and 6 to get 2.
4\times 32\left(8-10\right)^{6}-2^{10}\left(-1+3\right)^{3}
Calculate 2 to the power of 5 and get 32.
128\left(8-10\right)^{6}-2^{10}\left(-1+3\right)^{3}
Multiply 4 and 32 to get 128.
128\left(-2\right)^{6}-2^{10}\left(-1+3\right)^{3}
Subtract 10 from 8 to get -2.
128\times 64-2^{10}\left(-1+3\right)^{3}
Calculate -2 to the power of 6 and get 64.
8192-2^{10}\left(-1+3\right)^{3}
Multiply 128 and 64 to get 8192.
8192-1024\left(-1+3\right)^{3}
Calculate 2 to the power of 10 and get 1024.
8192-1024\times 2^{3}
Add -1 and 3 to get 2.
8192-1024\times 8
Calculate 2 to the power of 3 and get 8.
8192-8192
Multiply 1024 and 8 to get 8192.
0
Subtract 8192 from 8192 to get 0.