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-5\left(-2\right)^{4}\left(-3-5+8+2\right)\left(-4\right)
To multiply powers of the same base, add their exponents. Add 1 and 3 to get 4.
-5\times 16\left(-3-5+8+2\right)\left(-4\right)
Calculate -2 to the power of 4 and get 16.
-80\left(-3-5+8+2\right)\left(-4\right)
Multiply -5 and 16 to get -80.
-80\left(-8+8+2\right)\left(-4\right)
Subtract 5 from -3 to get -8.
-80\times 2\left(-4\right)
Add -8 and 8 to get 0.
-160\left(-4\right)
Multiply -80 and 2 to get -160.
640
Multiply -160 and -4 to get 640.