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Differentiate w.r.t. x
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\left(\frac{1}{x}\right)^{3}\times \left(\frac{1}{x}\right)^{3}
Use the rules of exponents to simplify the expression.
x^{-3}x^{-3}
To raise a power to another power, multiply the exponents.
x^{-3-3}
To multiply powers of the same base, add their exponents.
x^{-6}
Add the exponents -3 and -3.
\frac{\mathrm{d}}{\mathrm{d}x}(\left(\frac{1}{x}\right)^{6})
To multiply powers of the same base, add their exponents. Add 3 and 3 to get 6.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{1^{6}}{x^{6}})
To raise \frac{1}{x} to a power, raise both numerator and denominator to the power and then divide.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{1}{x^{6}})
Calculate 1 to the power of 6 and get 1.
-\left(x^{6}\right)^{-1-1}\frac{\mathrm{d}}{\mathrm{d}x}(x^{6})
If F is the composition of two differentiable functions f\left(u\right) and u=g\left(x\right), that is, if F\left(x\right)=f\left(g\left(x\right)\right), then the derivative of F is the derivative of f with respect to u times the derivative of g with respect to x, that is, \frac{\mathrm{d}}{\mathrm{d}x}(F)\left(x\right)=\frac{\mathrm{d}}{\mathrm{d}x}(f)\left(g\left(x\right)\right)\frac{\mathrm{d}}{\mathrm{d}x}(g)\left(x\right).
-\left(x^{6}\right)^{-2}\times 6x^{6-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-6x^{5}\left(x^{6}\right)^{-2}
Simplify.